Publikasjoner

Finanger T, Melby K, Spigset O, Andreassen TN, Lydersen S, Skråstad RB. Relationship between alcohol intake based on daily smartphone-reported consumption and PEth concentrations in healthy volunteers. Alcohol Alcohol. 2024 May 14;59(4):agae040. PMID: 38881524; PMCID: PMC11180986.

Gundersen POMG, Pasin D, Slørdal L, Spigset O, Josefsson M, Retrospective screening of new psychoactive substances (NPS) in post mortem samples from 2014 to 2021. 2024, Volume 361. 

Pedersen, H., Skliarova, T., Pedersen, S. A., Gråwe, R. W., Havnen, A., & Lara-Cabrera, M. L. (2024). Psychoeducation for adult ADHD: a scoping review about characteristics, patient involvement, and content. BMC psychiatry, 24(1), 73.

Skliarova, T., Pedersen, H., Holsbrekken, Å., Pedersen, S.A., Mandal, A., De Las Cuevas, C., Havnen, A., Gråwe, R.W., Lara-Cabrera, M.L. Psychoeducational group interventions for adults diagnosed with attention-deficit/hyperactivity disorder: a scoping review of feasibility, acceptability, and outcome measures. BMC Psychiatry, 2024, 24.1: 463. 

Hansen M, Havnen H, Andreassen TN, Spigset O, Hegstad S. Quantitative determination of R/S-methadone in human serum using ultra-high performance supercritical fluid chromatography-tandem mass spectrometry; a method for routine use. Drug Test Anal 2024; 16: 708-716. .

Krabseth HM, Strømmen M, Helland A, Spigset O. Effect of bariatric surgery on the pharmacokinetics of drugs used for attention deficit hyperactivity disorder (ADHD). Basic Clin Pharmacol Toxicol 2025, 136: e14099.

Helland A, Muller S, Spigset O, Krabset HM, Hansen M, Skråstad RB. Drug detection in oral fluid after low therapeutic doses of dexamphetamine, lisdelxamphetamine and methylphenidate in healthy volunteers. J Anal Toxicol 2024 Dec 19: bkae097. 

Hansen M, Havnen H, Andreassen TN, Spigset O, Hegstad S. Quantitative determination of R/S-methadone in human serum using ultra-high performance supercritical fluid chromatography-tandem mass spectrometry: A method for routine use. 2024 Apr 10.
 

Chalabianloo F, Fadnes LT, Johansson KA, Høiseth G, Vold JH, Kringen MK, Spigset O, Bramness JG. Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications. 2024 Mar;134(3):333-344. 

Skråstad RB, Aamo TO, Andreassen TN, Havnen H, Hveem K, Krokstad S, Salvesen Ø, Spigset O. Response to letter to editor for 'Quantifying alcohol consumption in the general population by analyzing phosphatidylethanol concentrations in whole blood: results from 24 574 subjects included in the HUNT4 study'. 2023 Jul 10;58(4):452. doi: 10.1093/alcalc/agad038.

Skråstad RB, Aamo TO, Andreassen TN, Havnen H, Hveem K, Krokstad S, Salvesen Ø, Spigset O. Quantifying Alcohol Consumption in the General Population by Analysing Phosphatidylethanol Concentrations in Whole Blood: Results from 24,574  Subjects Included in the HUNT4 Study. 2023 May 9;58(3):258-265. doi: 10.1093/alcalc/agad015.

Frost J, Gundersen POM, Brede WR, Gjerde S, Pleym H, Slørdal L. Findings of the neuromuscular blocking agent rocuronium in blood from deceased subjects several months after exposure: A report of two cases. Forensic Sci Int 2023 Jun; 347: 111680. doi: 10.1016/j.forsciint.2023.111680. Epub 2023 Apr 5.

Gjerde H, Frost J. Prevalence of alcohol and drugs among drivers killed in road traffic crashes in Norway during 2011-2020. Traffic Inj Prev 2023 Feb 10; 1-6. doi: 10.1080/15389588.2023.2174801. Online ahead of print.

Lauvsnes ADF, Hansen TI, Ankill SØ, Bae SW, Gråwe RW, Braund TA, Larsen M. Mobile assessments of mood, cognition, smartphone-based sensor activity, and variability in craving and substance use in patients with substance use disorders in Norway: Prospective observational feasibility study. JMIR Form Res 2023;7:e45254, doi:10.2196/45254

Bhad R., Achab S., et.al. (2023). An online global survey and follow-up expert groups on the scope and needs related to training, research, and mentorship among early-career addiction medicine professionals. Cambridge Prisms: Global Mental Health, 10, E44. doi:10.1017/gmh.2023.35

Melby K, Farokhnia M, et al. (2023). International perspectives on opioid use disorder and treatment: Results from an online convenience sample Heroin Addict Relat Clin Probl, 25(x): xx-xx. Published Ahead of Print August 21, 2023

Identification of unhealthy alcohol use by self-report and phosphatidylethanol (PEth) blood concentrations in an acute psychiatric department. Finanger T, Vaaler AE, Spigset O, Aamo TO, Andreassen TN, Gråwe RW, Skråstad RB. BMC Psychiatry. 2022 Apr 21;22(1):286.

Frost J, Helland A, Syrstad VEG, Aamo TO. Illegalt eller medisinsk amfetamin – hva er inntatt? Tidsskr Nor Laegeforen 2022 Jan 10; 142(1). doi: 10.4045/tidsskr.21.0743.

Melby K, Spigset O, Gråwe RW, Aamo TO, Quintana DS. The effect of intranasal oxytocin on processing emotional stimuli during alcohol withdrawal: A randomized placebo-controlled double-blind clinical trial. Horm Behav. 2022 Nov;146:105268. doi: 10.1016/j.yhbeh.2022.105268. Epub 2022 Oct 13. PMID: 36242831.

Lauvsnes ADF, Hansen TI, Håberg AK, Gråwe RW, Langaas M. Poor response inhibition and symptoms of inattentiveness are core characteristics of lifetime illicit substance use among young adults in the general Norwegian population: The HUNT study. Substance Use & Misuse: 2022, 57 (9). 

Lauvsnes ADF, Gråwe RW, Langaas M. Predicting relapse in substance use: prospective modeling based on intensive longitudinal data on mental health, cognition, and craving. Brain Sci: 2022, 12(7), 957.  

Roland PDH, Frost J. Melatonin: Økende bruk, men fortsatt manglende kunnskap om langtidseffekter og påvirkning på pubertetsutvikling. Nor Farmaceut Tidsskr 2022; 130(5): 38-9.

Finanger, T., Vaaler, A.E., Spigset, O. et al. Identification of unhealthy alcohol use by self-report and phosphatidylethanol (PEth) blood concentrations in an acute psychiatric department. BMC Psychiatry 22, 286 (2022). 

Skråstad RB, Spigset O, Aamo TO, Andreassen TN. Stability of phosphatidylethanol 16:0/18:1 in freshly drawn, authentic samples from healthy volunteers. J Anal Toxicol 2021; 45: 417-21. doi: 10.1093/jat/bkaa082.

Finanger T, Spigset O, Andreassen TN, Løkken TN, Gråwe RW, Aamo TO, Tømmervik K, Langås V, Salvesen KÅ, Skråstad RB. Phosphatidylethanol in blood as marker for alcohol consumption in early pregnancy: An observational study in 4067 pregnant women. Alcohol Clin Exp Res 2021; 45: 886-92. doi: 10.1111/acer.14577.

Lauvsnes ADF, Langaas M, Olsen A, Vassileva J, Spigset O, Gråwe RW. ADHD and mental health symptoms in the identification of young adult subjects with increased risk of alcohol dependency in the general population – The HUNT4 population study. Int J Environment Res Publ Health 2021; 18: doi.org/10.3390/ijerph182111601

Melby, Katrine; Nygård, Mona; Brobakken, Mathias Forsberg; Gråwe, Rolf W.; Guzey, Ismail Cuneyt; Reitan, Solveig Merete Klæbo; Vedul-Kjelsås, Einar; Heggelund, Jørn; Lara Cabrera, Mariela Loreto. Test-retest reliability of the patient activation measure-13 in adults with substance use disorders and schizophrenia spectrum disorders. Int J Enviromental Res and Public Health, 2021;DOI 10.3390/ijerph18031185

Aakerøy R, Brede WR, Stølen SB, Krabseth HM, Michelsen LS, Andreassen TN, Ader T, Frost J, Slettom G, Steihaug OM, Slørdal L. Severe Neurological Sequelae after a Recreational Dose of LSD. J Anal Toxicol. 2021 Aug 14; 45(7): e1-e3. doi: 10.1093/jat/bkaa145.

Havnen H, Hansen M, Spigset O, Hegstad S. Enantiomeric separation and quantification of R/S-amphetamine in serum using semi-automated liquid-liquid extraction and ultra-high performance supercritical fluid chromatography-tandem mass spectrometry. Drug Test Anal 2020; 12: 1344-1353. doi: 10.1002/dta.2879.

Toft A, Meisingset TW, Sæther SG. A young man with convulsive laughter. Tidsskr Nor Laegeforen. 2020 May 25. doi: 10.4045/tidsskr.19.0612. PMID: 32463185.

Krabseth H-M, Strømmen M, Spigset O, Helland A. Effect of sleeve gastrectomy on buprenorphine pharmacokinetics: a planned case observation. Clin Ther 2020; 42: 2232-7. doi: 10.1016/j.clinthera.2020.08.016.

Lauvsnes ADF, Langaas M, Toussaint P, Gråwe RW Mobile sensing in substance use research: A scoping review. Telemedicine and e-health, 2020 http://doi.org/10.1089/tmj.2019.0241

Melby K, Fasmer O, Henriksen TE, Gråwe RW, Aamo TO, Spigset O. Actigraphy assessment of motor activity and sleep in patients with alcohol withdrawal syndrome and the effects of intranasal oxytocin. PLOS ONE February 13, 2020 https://doi.org/10.1371/journal.pone.0228700

Ulvik M, Bratsberg NS, Nordrum IS, Frost J. Trends in forensic autopsy rates in Central Norway during the period 2007–2017: Can media attention impact autopsy practices? Forensic Sci Int: Reports Volume 2, December 2020, 100155

Frost J, Mikkelsen T. Fallgruver ved hurtigtester av rusmidler. Tidsskr Nor Laegeforen 2020 Sep 25; 140(14). doi: 10.4045/tidsskr.20.0696.

Bech AB, Clausen T, Waal H, Vindenes V, Edvardsen HE, Frost J, Skeie I. Post-mortem toxicological analyses of blood samples from 107 patients receiving opioid agonist treatment: substances detected and pooled opioid and benzodiazepine concentrations. Addiction 2020 Aug 1. doi: 10.1111/add.15211

Breivik H, Frost J, Løkken TN, Slørdal L. Post mortem tissue distribution of quetiapine in forensic autopsies. Forensic Sci Int 2020 Jul 24; 315: 110413.

Simonsen KW, Kriikku P, Thelander G, Edvardsen HE, Thordardottir S, Andersen CU, Jönsson AK, Frost J, Christoffersen DJ, Delaveris GJM, Ojanperä I. Fatal poisoning in drug addicts in the Nordic countries in 2017. Forensic Sci Int 2020 Aug; 313: 110343.

Breivik H, Løkken TN, Slørdal L, Frost J. A Validated Method for the Simultaneous Determination of Quetiapine, Clozapine and Mirtazapine in Postmortem Blood and Tissue Samples. J Anal Toxicol 2020 Apr 2; 44(5): 440-448.

Heldal AT, Aamo TO, Frost J. En kvinne i 40-årene som brukte vanedannende legemidler i svært høye doser. Tidsskr Nor Laegeforen 2020 Jan 2; 140(1).

Melby K, Gråwe RW, Aamo TO, Salvesen Ø, Spigset O. Effect of intranasal oxytocin on alcohol withdrawal syndrome: A randomized placebo-controlled double-blind clinical trial. Drug Alcohol Depend. 2019;197:95-101. doi:10.1016/j.drugalcdep.2019.01.003.

Dyrkorn R, Skråstad RB, Aamo TO. Bruk av fosfatidyletanol i førerkortsaker. Tidsskr Nor Laegeforen. 2019 Feb 11;139(3)

Frost J, Bernard JP, Dietrichs ES, Kjeldstadli K, Riedel B, Skråstad RB, Vevelstad M, Helland A. Nye anbefalinger ved serumkonsentrasjonsmålinger av sentralstimulerende legemidler. Tidsskr Nor Laegeforen 2019 Sep 23; 139(13).

Debernard KAB, Frost J, Roland PH. Kvetiapin er ikke en sovemedisin. Tidsskr Nor Laegeforen 2019 Sep 16; 139(13).

Valen A, Bogstrand ST, Vindenes V, Frost J, Larsson M, Holtan A, Gjerde H. Driver-related risk factors of fatal road traffic crashes associated with alcohol or drug impairment. Accid Anal Prev 2019 Oct; 131: 191-199.

Valen A, Bogstrand ST, Vindenes V, Frost J, Larsson M, Holtan A, Gjerde H. Fatally injured drivers in Norway 2005-2015-Trends in substance use and crash characteristics. Traffic Inj Prev 2019; 20(5): 460-466.

Chalabianloo F, Westin AA, Skogvoll E, Bramness JG, Spigset O. Methadone serum concentrations and influencing factors: a naturalistic observational study. Psychopharmacology 2019; 236: 3159-67.

Andreassen TN, Havnen H, Spigset O, Falch BMH, Skråstad R. Hight throughput UHPC-MSMS method for tha analysis of phosphatidylethanol (PEth) 16:0/18:1, a specific biomarker for alcohol consumption, in whole blood. J Anal Toxicol 2018; 42: 33-41.

Hegstad S, Havnen H, Helland A, Spigset O, Frost J. Enantiomeric separation and quantification of R/S-amphetamine in urine by ultra-high performance supercritical fluid chromatography tandem mass spectrometry. J Chromatography B 2018; 1077-8: 7-12.

Kaasbøll C, Hagen R, Gråwe RW. Population based associations between cannabis use, anxiety and depression in Norwegian adolescents. J Child & Adolescent Substance Abuse, 27 (4), 2018.  doi.org/10.1080/1067828X.2018.1462281

Serkland TT, Nygaard IL, Kvan E, Frost J, Aronsen L, Narum S, Bjånes T. Akutt telefonisk varsling om avvikende farmakologiske prøvesvar. Tidsskr Nor Laegeforen 2018 Nov 1; 138(18).

Hegstad S, Havnen H, Helland A, Spigset O, Frost J. Enantiomeric separation and quantification of R/S-amphetamine in urine by ultra-high performance supercritical fluid chromatography tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2018; 1077-1078: 7-12.

Hegstad S, Kristoffersen L, Liane VH, Spigset O. EtG and EtS in autopsy blood samples with and without putrefaction using UHPLC-MS-MS. J Anal Toxicol 2017; 41: 107-13.

Hegstad S, Helland A, Hagemann C, Spigset O. EtG/EtS in serum by UHPLC-MS-MS in suspected sexual assault cases. J Anal Toxicol, 2017; 41: 618-22.

Andersson H. W., Otterholt E., Gråwe R.W. Patient satisfaction with treatments and outcomes in residential addiction institutions. Nordic Studies on Alcohol and Drugs, 2017, vol. 34 (5): 375-384

Edvardsen HM, Tverborgvik T, Frost J, Rogde S, Morild I, Waal H, Clausen T, Slørdal L, Vindenes V. Differences in combinations and concentrations of drugs of abuse in fatal intoxication and driving under the influence cases. Forensic Sci Int 2017; 281: 127-133.

Strømmen M, Helland A, Kulseng B, Spigset O. Increased bioavilabiliby of methadone following sleeve gastrectomy – a plassned case observation. Clin Ther 2016; 38: 1532-6.

Aakerøy R, Skråstad RB, Helland A, Hilberg H, Aamo T, Dyrkorn R, Spigset O. Nye markører for påvisning av alkoholbruk. Tidsskr Nor Legeforen 2016; 136: 1643-7.

Gråwe R W. Kunnskapsbasert behandling av personer med ROP-lidelser. I Gråwe RW (red.) Kombinerte behandlingstiltak til personer med samtidig rus- og psykisk lidelse: kunnskapsbaserte behandlingstiltak innen rus- og avhengighetsmedisin, 2016, side 17-34. Fagbokforlaget, Trondheim, Norge.

Gråwe R W. Kartlegging og diagnostisering av personer med ROP-lidelser. I Gråwe RW (red.) Kombinerte behandlingstiltak til personer med samtidig rus- og psykisk lidelse: kunnskapsbaserte behandlingstilt ak innen rus- og avhengighetsmedisin, 2016, side 35-50. Fagbokforlaget, Trondheim, Norge.

Gråwe R W. Motiverende tiltak til personer med ROP-lidelser. I Gråwe RW (red.) Kombinerte behandlingstiltak til personer med samtidig rus- og psykisk lidelse: kunnskapsbaserte behandlingstiltak innen rus- og avhengighetsmedisin, 2016, side 51-66. Fagbokforlaget, Trondheim, Norge.

Gråwe R W. Kognitiv atferdsterapi mot rusmiddelbruk og psykiske lidelser. I Gråwe RW (red.) Kombinerte behandlingstiltak til personer med samtidig rus- og psykisk lidelse: kunnskapsbaserte behandlingstiltak innen rus- og avhengighetsmedisin, 2016, side 67-92. Fagbokforlaget, Trondheim, Norge.

Gråwe R W. familie- og pårørendetiltak til personer med rus og psykiske lidelser. I Gråwe RW (red.) Kombinerte behandlingstiltak til personer med samtidig rus- og psykisk lidelse: kunnskapsbaserte behandlingstiltak innen rus- og avhengighetsmedisin, 2016, side 153-166. Fagbokforlaget, Trondheim, Norge 1.  

Gråwe R W. Integrerte psykososiale behandlingstiltak for personer med rusmiddellidelser og samtidig angst og depresjon. I Gråwe RW (red.) Kombinerte behandlingstiltak til personer med samtidig rus- og psykisk lidelse: kunnskapsbaserte behandlingstiltak innen rus- og avhengighetsmedisin, 2016, side 167-212. Fagbokforlaget, Trondheim, Norge.

Gråwe R W. Sentrale tiltak i pasientforløpet hos personer med ROP-lidelser. I Gråwe RW (red.) Kombinerte behandlingstiltak til personer med samtidig rus- og psykisk lidelse: kunnskapsbaserte behandlingstiltak innen rus- og avhengighetsmedisin, 2016, side 213 -238. Fagbokforlaget, Trondheim, Norge 

Gråwe R W. Bruk av tvang og behandling i rusakutt for personer med ROP-lidelser. I Gråwe RW (red.) Kombinerte behandlingstiltak til personer med samtidig rus- og psykisk lidelse: kunnskapsbaserte behandlingstiltak innen rus- og avhengighetsmedisin, 2016, side 239-257. Fagbokforlaget, Trondheim, Norge.

Frost J, Løkken TN, Helland A, Nordrum IS, Slørdal L. Post-mortem levels and tissue distribution of codeine, codeine-6-glucuronide, norcodeine, morphine and morphine glucuronides in a series of codeine-related deaths. Forensic Sci Int 2016 262: 128-37

Karlsen Bjånes T, Mjåset Hjertø E, Lønne L, Aronsen L, Andsnes Berg J, Bergan S, Otto Berg-Hansen G, Bernard JP, Larsen Burns M, Toralf Fosen J, Frost J, Hilberg T, Krabseth HM, Kvan E, Narum S, Austgulen Westin A. Pharmacology Portal: An Open Database for Clinical Pharmacologic Laboratory Services. Clin Ther 2016; 38: 222-6.

Westin AA, Frost J, Brede WR, Gundersen PO, Einvik S, Aarset H, Slørdal L. Sudden Cardiac Death Following Use of the Synthetic Cannabinoid MDMB-CHMICA. J Anal Toxicol 2016; 40: 86-7.